No transfer today which I frankly suspected. The indication all along was a 5 day transfer and I feel better about that.
We didn't lose any last night, although one has only divided into 3 cells, so it will probably arrest. The remainder are:
4 four cell
1 five cell
2 six cell and
4 eight cell
This isn't mine, but this is what an 8 cell looks like:
Was so happy to see some 8 cell in the mix. If they all make it to Sat, that means we can have three ledt over for FET tries.
They are all a grade 2. I asked her if there was anything to indicate the quality yet, and she didn't really have a good answer for me. I know grade 1 is the best, and grade 4 the worst, but still don't really know much other than some, not all are starting to show signs of fragmentation.
Fragmentation is when the cells divide unevenly leaving some leftover over "junk" cytoplasm. The higher level of fragmentation, the lower chances of pregnancy. Anything with a grade of 3 or 4 is highly fragmented and likely won't make it to blastocyst stage.
Here's a visual on the grading:
I wish I knew more about how each one graded, but they seemed kind of busy today. I know now what they meant by waiting on pins and needles for the embryologist report. It's going to be a long time til Sat morning!!!
Thursday, 16 May 2013
Wednesday, 15 May 2013
2 days post egg retrieval
Not a lot to report today, 2 days after the retrieval. Embryology called early, around 7:45 to report that of the 15 eggs that fertilized 12 had survived and cells were dividing normally. We again had the discussion about not wanting twins and she marked it in the file as there are three embryologists there.
She advised that they would tentatively schedule a transfer for tomorrow just in case. But she did seem to echo that because we only want to transfer 1, it will most likely be Sat. I find out tomorrow morning at 8am if we're a go.
I did wake up feeling significantly better. I was glad I had showered the night before because while I was feeling better, I was still achey and I had to make some eggs for my share of the breakfast.
That was easy...spray non stick spray in a muffin tin, crack in eggs, add some leftover diced ham and a sprinkle of cheese, bake for 10 minutes in a preheated 350 oven.
After the meeting, I was really worn out and feeling pain again, so I came home and did nothing but drop off and pick up preschool, and order pizza online.
and so ends cd 28.
She advised that they would tentatively schedule a transfer for tomorrow just in case. But she did seem to echo that because we only want to transfer 1, it will most likely be Sat. I find out tomorrow morning at 8am if we're a go.
I did wake up feeling significantly better. I was glad I had showered the night before because while I was feeling better, I was still achey and I had to make some eggs for my share of the breakfast.
That was easy...spray non stick spray in a muffin tin, crack in eggs, add some leftover diced ham and a sprinkle of cheese, bake for 10 minutes in a preheated 350 oven.
After the meeting, I was really worn out and feeling pain again, so I came home and did nothing but drop off and pick up preschool, and order pizza online.
and so ends cd 28.
The "little" wait
So the day after retrieval, I was definitely sore. I was able to get up and make a simple breakfast and pack lunches, but I was grateful for Rob's assistance with this.
Embryology called to let me know 15 of the 22 eggs fertilized. They wanted to know if we were transferring 1 or 2 and I said, "that kind of depends on what you tell us about the embryo's." I made it clear we really didn't want twins, so were leaning toward one. But at the same time, wanted the best chance. She said, based on that, they would probably lean towards a 5 day transfer but we would just have to wait and see.
They had said I could "go back to work" but I just don't see how anybody really could. I mean, it wasn't pain like my c-section, but it was still tough to move around, bend over, walk very much. I had so much going on that day....DAisy girls scouts (I am the leader), Set up for MOPS (I was supose to show the new coordinators for the next year what to do) and Josh's string concert.
Nope, nope and NOPE!
I stayed home and rested. I got up just enough to feed myself and Noah. Pulled a pre-cooked sliced ham from the freezer and called that dinner and rested. I just wasn't up to it.
I was starting to get frustrated by not feeling much better, so I called another MOPS mom who I knew had been through IVF a couple of times to get her thoughts and experiences. I felt so much better after because everything she described was exactly what I was feeling. The bloat is unbelievable. For those of you who have been pregnant, it's like that really heavy pressure you feel below your tummy during the last month of your pregnancy.... And there is so much stimulation, it presses against your bladder, so you have to go to the bathroom every 10 minutes. And since you are suppose to drink 80 oz of water it ends up you need to pee every 5 minutes.
I was hoping I would feel better the next day, so I could go to the last Mops meeting of the year before summer break. and I was looking forward to seeing how many son to be embryos would survive the night. They said the wait for that can be brutal, but that's OK. It's just a little wait. The big wait will be the "dreaded 2ww."And so ends cd 27.
Embryology called to let me know 15 of the 22 eggs fertilized. They wanted to know if we were transferring 1 or 2 and I said, "that kind of depends on what you tell us about the embryo's." I made it clear we really didn't want twins, so were leaning toward one. But at the same time, wanted the best chance. She said, based on that, they would probably lean towards a 5 day transfer but we would just have to wait and see.
They had said I could "go back to work" but I just don't see how anybody really could. I mean, it wasn't pain like my c-section, but it was still tough to move around, bend over, walk very much. I had so much going on that day....DAisy girls scouts (I am the leader), Set up for MOPS (I was supose to show the new coordinators for the next year what to do) and Josh's string concert.
Nope, nope and NOPE!
I stayed home and rested. I got up just enough to feed myself and Noah. Pulled a pre-cooked sliced ham from the freezer and called that dinner and rested. I just wasn't up to it.
I was starting to get frustrated by not feeling much better, so I called another MOPS mom who I knew had been through IVF a couple of times to get her thoughts and experiences. I felt so much better after because everything she described was exactly what I was feeling. The bloat is unbelievable. For those of you who have been pregnant, it's like that really heavy pressure you feel below your tummy during the last month of your pregnancy.... And there is so much stimulation, it presses against your bladder, so you have to go to the bathroom every 10 minutes. And since you are suppose to drink 80 oz of water it ends up you need to pee every 5 minutes.
I was hoping I would feel better the next day, so I could go to the last Mops meeting of the year before summer break. and I was looking forward to seeing how many son to be embryos would survive the night. They said the wait for that can be brutal, but that's OK. It's just a little wait. The big wait will be the "dreaded 2ww."And so ends cd 27.
The Big day: Egg Retrieval!
I had set two alarms to go off at 6:00 so we could leave by 6:45 for our 8:30 retrieval. I didn't have much to do. I had showered the night before, and I wasn't allowed to eat, drink, wear makeup or jewelry. So I got dressed, took the nail polish off (so anesthesiology could watch my color) and freshened up my hair, and sat to wait for hubby.
The drive was uneventful and because we left so early, we had a bit of a wait. (the only way to get there is a very unpredictable freeway that has a habit of bottlenecking when you least need it to!). Once they called my name, they were again, super sweet and gentle. I again went to the changing room to strip down, gown up, get my little footies on and hair cover. Then I went to my cubicle with my nice warmed hospital blanket.
can I just say again, I want one of those blanket warmers!
So they spent about a half hour taking some more medical history, taking vitals and then setting up the iv line for the anesthesia. AS usual, they couldn't find a vein, my right arm which was always so easy is completely scared (the veins, not the outside skin) and the left is so hard. She tried my left hand, it bled all over and then burned whenever they ran fluid so out that came. Then they tried my right hand - nope! Right arm again? nope, just too scarred. Finally on the fourth try, they got my left arm. In their defense, I really am a hard stick. So was my mom, so was my grandma (I'll have to ask my sister if she is as well!)
Then it was hurry up and wait. While I was initially very nervous, I calmed quickly. AFter all, they were putting me out for the hard part, right? I mean, how bad could it be?
In the mean time....TMI report - the usual protocol is for the Dad to provide the sample for fertilization AT the surgical center. But because we lived within an hour, DH was allowed to do this at home. I pushed for this because for obvious reasons, that part of it makes Dh really uncomfortable. Thank goodness I did, because they didn't realize he had brought it, and started to show him to the room. It was awful! Very clinical, a pad on the chair and a tv on the wall. Um, ewe. He said another Dad to be was walking "the walk of shame" either into or out of the room. Wheh....so glad I was able to push for him to do at home!
When it was my time, they walked me into the OR and I took my seat on the deluxe stirrup table - yay me- I described for the hysteroscopy. The only difference this time was they strapped my legs to the stirrups, I'm guessing so I couldn't fall off the table since I would be out.
At the point, the anesthesiologist told me she was starting and I would start to feel woozy or dizzy. Somewhere right in between was what I felt. I remember wondering what I should do. I was very sleep from not sleeping the night before, or was that the meds? I didn't want to fall asleep on them if they had more questions. Then the anesthesiologist said she was going to give me the next medicine and shortly thereafter I was out. I don't even remember Dr. G coming in.
What I do remember is them calling my name and telling it was time to wake up. I woke up pretty easily and was just a but unsteady on my feet. They walked me to my chair and had me just slowly recover. Thank goodness Rob was allowed to come back and sit with me. I felt very emotional and was crying but that was more because I just needed my husband, and we were having a tough time at the moment (not for a public forum, sorry!) I did feel sore and bloated, but not in a really bad way. I felt like I could bear it pretty easily.
They told me almost immediately that they were able to retrieve 22 eggs! Wow! That is just fantastic, from what I understand, for a woman my age. I was over the moon happy!
Rob had a lot of questions though, but my Dr. G is such a great man, so kind. He said, he had to do the next patient, but to just give him a few minutes and he would talk with him. It was a retrieval for someone else, so he had to go but when he came back in about 15 minutes, he pulled a chair over and gave Rob his undivided attention. He didn't leave til all Rob's questions were answered. I'm telling you, if you're in Phila area, go see Dr. Gocial, RMA of Philadelphia.
After that, Rob seemed more at peace with the responses and it was time to go home. He helped me get dressed - I was tender for sure, but OK. Then they had Rob pull the car around to a side entrance that was easier for me to get to, and they walked me to the car. After that, it was 24 hours of strict bed rest - bathroom breaks only.
I was definitely achey, and really tired, so I spent most of the day sleeping. I started the antibiotic and anti-rejection medicines that day - the end of cd 26.
The drive was uneventful and because we left so early, we had a bit of a wait. (the only way to get there is a very unpredictable freeway that has a habit of bottlenecking when you least need it to!). Once they called my name, they were again, super sweet and gentle. I again went to the changing room to strip down, gown up, get my little footies on and hair cover. Then I went to my cubicle with my nice warmed hospital blanket.
can I just say again, I want one of those blanket warmers!
So they spent about a half hour taking some more medical history, taking vitals and then setting up the iv line for the anesthesia. AS usual, they couldn't find a vein, my right arm which was always so easy is completely scared (the veins, not the outside skin) and the left is so hard. She tried my left hand, it bled all over and then burned whenever they ran fluid so out that came. Then they tried my right hand - nope! Right arm again? nope, just too scarred. Finally on the fourth try, they got my left arm. In their defense, I really am a hard stick. So was my mom, so was my grandma (I'll have to ask my sister if she is as well!)
Then it was hurry up and wait. While I was initially very nervous, I calmed quickly. AFter all, they were putting me out for the hard part, right? I mean, how bad could it be?
In the mean time....TMI report - the usual protocol is for the Dad to provide the sample for fertilization AT the surgical center. But because we lived within an hour, DH was allowed to do this at home. I pushed for this because for obvious reasons, that part of it makes Dh really uncomfortable. Thank goodness I did, because they didn't realize he had brought it, and started to show him to the room. It was awful! Very clinical, a pad on the chair and a tv on the wall. Um, ewe. He said another Dad to be was walking "the walk of shame" either into or out of the room. Wheh....so glad I was able to push for him to do at home!
When it was my time, they walked me into the OR and I took my seat on the deluxe stirrup table - yay me- I described for the hysteroscopy. The only difference this time was they strapped my legs to the stirrups, I'm guessing so I couldn't fall off the table since I would be out.
At the point, the anesthesiologist told me she was starting and I would start to feel woozy or dizzy. Somewhere right in between was what I felt. I remember wondering what I should do. I was very sleep from not sleeping the night before, or was that the meds? I didn't want to fall asleep on them if they had more questions. Then the anesthesiologist said she was going to give me the next medicine and shortly thereafter I was out. I don't even remember Dr. G coming in.
What I do remember is them calling my name and telling it was time to wake up. I woke up pretty easily and was just a but unsteady on my feet. They walked me to my chair and had me just slowly recover. Thank goodness Rob was allowed to come back and sit with me. I felt very emotional and was crying but that was more because I just needed my husband, and we were having a tough time at the moment (not for a public forum, sorry!) I did feel sore and bloated, but not in a really bad way. I felt like I could bear it pretty easily.
They told me almost immediately that they were able to retrieve 22 eggs! Wow! That is just fantastic, from what I understand, for a woman my age. I was over the moon happy!
Rob had a lot of questions though, but my Dr. G is such a great man, so kind. He said, he had to do the next patient, but to just give him a few minutes and he would talk with him. It was a retrieval for someone else, so he had to go but when he came back in about 15 minutes, he pulled a chair over and gave Rob his undivided attention. He didn't leave til all Rob's questions were answered. I'm telling you, if you're in Phila area, go see Dr. Gocial, RMA of Philadelphia.
After that, Rob seemed more at peace with the responses and it was time to go home. He helped me get dressed - I was tender for sure, but OK. Then they had Rob pull the car around to a side entrance that was easier for me to get to, and they walked me to the car. After that, it was 24 hours of strict bed rest - bathroom breaks only.
I was definitely achey, and really tired, so I spent most of the day sleeping. I started the antibiotic and anti-rejection medicines that day - the end of cd 26.
22....
So a lot has happened since Friday. It's just been busy, and I'm uncomfortable and frankly, sometimes you just have to step away from all this stuff to maintian your sanity, kwim?
So Saturday, I went in for another blood draw and scan and I was greeted with "looks like we're ready to discharge you."
Huh?
Am I through? Was the whole thing a bust after all? No, no, thank goodness. All that meant was, is they thought I was ready and that I would probably have the retrieval Monday instead of Tues. So I would get the call later to determine would I take cetrotide (don't ovulate) or Pregnyl (hcg trigger). I was hoping it was the later because frankly, I didn't want to take that big old nasty cetrotide injection again.....
As it turns out, it was the later, so while I took menopur that Sat morning, I did not take the Gonal F or Cetrotide, but rather the HCG trigger that night at 8:30 so that 36 hours later, at precisely 8:30 Monday morning, I would ovulate and they could retriece the eggs....
That trigger has always made me nervous....I mean, it is so exact...How did they know exactly at 8:30 I'd be ready? What if I was ready at 7:30 and they missed it? While I didn't want to take it, it was so hard not to take the cetrotide... or to call the dr and say, how about a half dose? I had to sit back and just trust my dr.
Sunday morning I went in just for blood work. At this point, I must share that my arms are black and blue and i look a bit like a junkie. But they wanted to make sure everything was still on track, and that there was HCG in my system. Actually, the way she said it was, "we want to make sure you took the shot correctly?"
Huh? (scratching my head....) I've taken how many up until now, and you want to check this one? Hey, whatever, they're the experts! And it was Mother's Day, and we had to stuff to do, so short appointments are always good. Quick in and out.
So, after the Mother's Day festivities (thank you to my sweet SIL, Christine who organized a lovely barbecue with awesome food....) I packed the kids up and dropped them off at my dad's to spend the night. We were going to have to leave at 6:45 the next morning, and they all had school.....I have a great dad who got them all where they needed to be.
And then home to NOT sleep the night before the transfer.... (does anyone I wonder?)
So Saturday, I went in for another blood draw and scan and I was greeted with "looks like we're ready to discharge you."
Huh?
Am I through? Was the whole thing a bust after all? No, no, thank goodness. All that meant was, is they thought I was ready and that I would probably have the retrieval Monday instead of Tues. So I would get the call later to determine would I take cetrotide (don't ovulate) or Pregnyl (hcg trigger). I was hoping it was the later because frankly, I didn't want to take that big old nasty cetrotide injection again.....
As it turns out, it was the later, so while I took menopur that Sat morning, I did not take the Gonal F or Cetrotide, but rather the HCG trigger that night at 8:30 so that 36 hours later, at precisely 8:30 Monday morning, I would ovulate and they could retriece the eggs....
That trigger has always made me nervous....I mean, it is so exact...How did they know exactly at 8:30 I'd be ready? What if I was ready at 7:30 and they missed it? While I didn't want to take it, it was so hard not to take the cetrotide... or to call the dr and say, how about a half dose? I had to sit back and just trust my dr.
Sunday morning I went in just for blood work. At this point, I must share that my arms are black and blue and i look a bit like a junkie. But they wanted to make sure everything was still on track, and that there was HCG in my system. Actually, the way she said it was, "we want to make sure you took the shot correctly?"
Huh? (scratching my head....) I've taken how many up until now, and you want to check this one? Hey, whatever, they're the experts! And it was Mother's Day, and we had to stuff to do, so short appointments are always good. Quick in and out.
So, after the Mother's Day festivities (thank you to my sweet SIL, Christine who organized a lovely barbecue with awesome food....) I packed the kids up and dropped them off at my dad's to spend the night. We were going to have to leave at 6:45 the next morning, and they all had school.....I have a great dad who got them all where they needed to be.
And then home to NOT sleep the night before the transfer.... (does anyone I wonder?)
Friday, 10 May 2013
Big needle = Big fear
So I had my blood work this morning, and another ultrasound. All went well, My E2 was around 1600, continually on the rise, and p4 had risen to 2.63, LH stayed the same, around7.5. What does all that mean? Hell if I know, but apparently it tells Dr. G to start the cetrotide.
Cetrotide does the same thing as ganirelex or Lupron. Since some of the follicles are really starting to mature, the worse thing would be that I ovulate now, with like 10 eggs or something crazy like that. So the cetrotide shuts down my pituitary gland from sending the "green light" hormone to ovulate.
The needle scared me to death. It wasn't a half inch like the others I've been using, but more like a full inch. But it has to to be done, and Rob is away on a business trip, so I gritted my teeth and got the job done myself. At these times, I cheer-lead myself saying, it's all for a greater cause, and will be so worth it if we succeed. It helps anyway. I remember my IVF nurse telling me not to do it on the same side as the Gonal F or they could interact in some way. So to be safe, I opted to do it in my thigh.
Again, that big needle scared me (I am so glad they have worked these injections into sub-cu rather than intramuscular. I simply cannot imagine getting stuck with those huge 27 gauge needles every day!) I knew right away I was going to try the icing trick. It did work, while I did jam the needle down with a little more force, I did not feel it go in at all, nor the medicine like I do the menopur. But now, after 10 minutes, and the my leg is warming up - it feels very sore and tender.
Speaking of sore and tender, that's me. My ovaries are completed enlarged and stimmed and I really hurt. No walking in the gym today, although I tried. Bending over is too much, walking fast is too much, so I just kind of hobble about. There was a little fluid on the scan, but not anything to worry about, or so I was told. But my ovaries are now "kissing" ovaries. They are so heavy, they are kind of flopping over each other and touching. Nice, I hope they are encouraging each other on!
One quick funny bit...I saw another dr this morning, not one I often see. She just doesn't come up on the rotation for me that often. The minute she walked in, the first thing she says before anything else is, "how old are you?" I very sheepishly admitted I was 44. I thought she was going to give me grief because of the whole advanced maternal age thing.... but that wasn't it at all. She said I am responding so well (or rather my ovaries are) that she thought my chart was wrong. In her words "You're not responding like a 44 year old usually does." I said that's good, right? And she affirmed that it was a good thing. Even the IVF nurse agreed and said "You're not even on a really big dose either!" She (the dr.) said she can't make any guarantee about eggs, but my ovaries were really good. I found it really encouraging anyway. Hopefully that means they can get tons of good eggs to work with.
On the way home, thinking about that morning's appointment, I couldn't help but think that the gluten free diet had to have contributed to this good outcome. I can't prove it, have no scientific fact behind it, I just feel it in my gut.
So today's shots include 3 vials menopur in the morning, back to 225 Gonal-F in the evening, and add .25 mg o f cetrotide. And they want to see me again tomorrow, so I am guessing this starts the daily monitoring they mentioned would come just before retrieval.
I am trying to think positive. I could be pregnant in slightly over 2 weeks. Oh my gosh, I really hope so!
And so ends cycle day 23.
Cetrotide does the same thing as ganirelex or Lupron. Since some of the follicles are really starting to mature, the worse thing would be that I ovulate now, with like 10 eggs or something crazy like that. So the cetrotide shuts down my pituitary gland from sending the "green light" hormone to ovulate.
The needle scared me to death. It wasn't a half inch like the others I've been using, but more like a full inch. But it has to to be done, and Rob is away on a business trip, so I gritted my teeth and got the job done myself. At these times, I cheer-lead myself saying, it's all for a greater cause, and will be so worth it if we succeed. It helps anyway. I remember my IVF nurse telling me not to do it on the same side as the Gonal F or they could interact in some way. So to be safe, I opted to do it in my thigh.
Again, that big needle scared me (I am so glad they have worked these injections into sub-cu rather than intramuscular. I simply cannot imagine getting stuck with those huge 27 gauge needles every day!) I knew right away I was going to try the icing trick. It did work, while I did jam the needle down with a little more force, I did not feel it go in at all, nor the medicine like I do the menopur. But now, after 10 minutes, and the my leg is warming up - it feels very sore and tender.
Speaking of sore and tender, that's me. My ovaries are completed enlarged and stimmed and I really hurt. No walking in the gym today, although I tried. Bending over is too much, walking fast is too much, so I just kind of hobble about. There was a little fluid on the scan, but not anything to worry about, or so I was told. But my ovaries are now "kissing" ovaries. They are so heavy, they are kind of flopping over each other and touching. Nice, I hope they are encouraging each other on!
One quick funny bit...I saw another dr this morning, not one I often see. She just doesn't come up on the rotation for me that often. The minute she walked in, the first thing she says before anything else is, "how old are you?" I very sheepishly admitted I was 44. I thought she was going to give me grief because of the whole advanced maternal age thing.... but that wasn't it at all. She said I am responding so well (or rather my ovaries are) that she thought my chart was wrong. In her words "You're not responding like a 44 year old usually does." I said that's good, right? And she affirmed that it was a good thing. Even the IVF nurse agreed and said "You're not even on a really big dose either!" She (the dr.) said she can't make any guarantee about eggs, but my ovaries were really good. I found it really encouraging anyway. Hopefully that means they can get tons of good eggs to work with.
On the way home, thinking about that morning's appointment, I couldn't help but think that the gluten free diet had to have contributed to this good outcome. I can't prove it, have no scientific fact behind it, I just feel it in my gut.
So today's shots include 3 vials menopur in the morning, back to 225 Gonal-F in the evening, and add .25 mg o f cetrotide. And they want to see me again tomorrow, so I am guessing this starts the daily monitoring they mentioned would come just before retrieval.
I am trying to think positive. I could be pregnant in slightly over 2 weeks. Oh my gosh, I really hope so!
And so ends cycle day 23.
Thursday, 9 May 2013
Just keep swimming, swimming swimming swimming....
Any Nemo fans out there? Remember Dory singing "just keep swimming?" That's a little how I feel right now. Just plodding along, taking my injections and going in every other day for blood work and ultra sounds.
This week has been uneventful, really, if you don't count the anxiety and anxiousness I keep stuffing down throughout this process. Monday I was a bit anxious because there didn't seem to be any activity. Those old fears came out in full force - What if it didn't work? What if I am one of those people who don't respond? I mean the clomid doesn't really work for me anymore, maybe these won't either?
Then Wednesday, I had a bit of an issue. Ever have one of those mornings where you just can't do anything right? That was me...with my Menopur - yikes! At $70 per vial, it was not easily overlooked. I goofed up the steps and tried to take the vial off the Q-cap before filling the syringe with the medicine, so I lost half of it. Ended up using another vial. Then, to make matters worse, I must not have screwed on the injection tip properly because although the needle was firmly in my belly, the medicine seemed to be slowly, actually quite liberally running down my stomach.
Double yikes!
I had blood work and another scan that morning, so I told Dr. G what had happened and thank goodness, it was no big deal. He said it stays in your body about 36 hours, so one missed dose was OK. After the scan, he actually said it might have ben fortuitous as those follicles had finally started to grow! He said after seeing the blood work, he may just reduce my dosage.
That's exactly what happened. I am down to 150 IU of Gonal-F but still the 3 vials of Menopur daily.
Side effects seem to change daily. The dizziness and bruising is much better. (Icing the injection point prior has helped tremendously with the pain and bruising). But I am still fatigued is not listed as a side effect. I get headaches, my joints hurt a bit, I have a sore throat and runny nose, my breasts and ovaries hurt and I am starting in with nausea. But none are severe enough to make me miserable. But I am anxious to be done with this part of the process and on to retrieval.
The one concern I have (TMI alert!!!!) is that things are starting to flow down south in the girly bits. I am clearly getting what's considered fertile Cervical mucous and of course, Rob is in Atlanta for the day and won't be back til tomorrow night. I am hoping beyond hope that I don't ovulate between now and tomorrow, and I will ask about it. I know in my hoard of medicines they prescribed, I have three boxes of cetrotide. Maybe I will start this tomorrow? (yay, more shots....)
Tomorrow is another blood draw and scan. I am hoping they will have a better idea of the retrieval which has been "guestimated" at this point, for Tuesday, 5 days from now.
And so ends cd 22.
This week has been uneventful, really, if you don't count the anxiety and anxiousness I keep stuffing down throughout this process. Monday I was a bit anxious because there didn't seem to be any activity. Those old fears came out in full force - What if it didn't work? What if I am one of those people who don't respond? I mean the clomid doesn't really work for me anymore, maybe these won't either?
Then Wednesday, I had a bit of an issue. Ever have one of those mornings where you just can't do anything right? That was me...with my Menopur - yikes! At $70 per vial, it was not easily overlooked. I goofed up the steps and tried to take the vial off the Q-cap before filling the syringe with the medicine, so I lost half of it. Ended up using another vial. Then, to make matters worse, I must not have screwed on the injection tip properly because although the needle was firmly in my belly, the medicine seemed to be slowly, actually quite liberally running down my stomach.
Double yikes!
I had blood work and another scan that morning, so I told Dr. G what had happened and thank goodness, it was no big deal. He said it stays in your body about 36 hours, so one missed dose was OK. After the scan, he actually said it might have ben fortuitous as those follicles had finally started to grow! He said after seeing the blood work, he may just reduce my dosage.
That's exactly what happened. I am down to 150 IU of Gonal-F but still the 3 vials of Menopur daily.
Side effects seem to change daily. The dizziness and bruising is much better. (Icing the injection point prior has helped tremendously with the pain and bruising). But I am still fatigued is not listed as a side effect. I get headaches, my joints hurt a bit, I have a sore throat and runny nose, my breasts and ovaries hurt and I am starting in with nausea. But none are severe enough to make me miserable. But I am anxious to be done with this part of the process and on to retrieval.
The one concern I have (TMI alert!!!!) is that things are starting to flow down south in the girly bits. I am clearly getting what's considered fertile Cervical mucous and of course, Rob is in Atlanta for the day and won't be back til tomorrow night. I am hoping beyond hope that I don't ovulate between now and tomorrow, and I will ask about it. I know in my hoard of medicines they prescribed, I have three boxes of cetrotide. Maybe I will start this tomorrow? (yay, more shots....)
Tomorrow is another blood draw and scan. I am hoping they will have a better idea of the retrieval which has been "guestimated" at this point, for Tuesday, 5 days from now.
And so ends cd 22.
Monday, 6 May 2013
Just another step down the IVF trail....
There's not much to report at this stage of the game. For the past two days, I've just given myself the injections of Gonal-F at night (225IU) and Menopur in the morning (3 vials). This morning (cd 19 if you are keeping track) I had another bloodwork draw and scan. Dr. G commented that my lining was thin but that kind of makes sense.... I've been spotting since stopping the bcp's. Only just stopped spotting yesterday. He said we will just have to wait and see what the bloodwork reveals.
It revealed that my estrogen was 400 something and that I would continue on the current levels of injections until Wed morning at which time I will have more bloodwork and another scan.
I can tell you that while the needles are the same size as those used for insulin, the medication inside is not. All I can say is OUCH.
This is the assortment I use to mix the menopur.
I don't actually use the long needle at all, just the syringe part of it. I screw off the needle end, and screw on the clear plastic "Q-cap" to mix everything. Then I screw off the Q-cap and screw on the half inch needle for the actual injection.
Honestly, sticking the needle in does not hurt at all, at least not me. What hurts is the medicine (menopur the most) going in. It burns and I can feel it spreading. I have found that icing the area before hand helps tremendously. The tonal-F is not nearly as bad. But my IVF nurse had given me the advice to let the filled syringe sit for 10 minutes to come to room temp. I have done this and the pain is minimal.
But my tummy really hurts. I really do feel like a pin cushion. It feels slightly swollen, but hugely bruised. I am wearing looser clothing so as not to rub up against the area. Side effects are not too bad....some headaches and dizziness but only when I bend over, like to tie my shoe. And emotional. I feel like I want to cry over the silliest little things. Trying to keep that in check so as not to make my husband crazy.
Is it difficult? yes. Unbearable? No. I don't like it, but so far, it's nothing I can't handle. Still not trying to worry about if I will have enough eggs retrieved to do this, still not thinking about getting through all the cycles in my package and not getting pregnant. I have been searching my heart...Is this really worth it? Do I really want another baby. I can honestly and sincerely say yes. I want it as badly as ever.
And so ends cd 19.
It revealed that my estrogen was 400 something and that I would continue on the current levels of injections until Wed morning at which time I will have more bloodwork and another scan.
I can tell you that while the needles are the same size as those used for insulin, the medication inside is not. All I can say is OUCH.
This is the assortment I use to mix the menopur.
I don't actually use the long needle at all, just the syringe part of it. I screw off the needle end, and screw on the clear plastic "Q-cap" to mix everything. Then I screw off the Q-cap and screw on the half inch needle for the actual injection.
Honestly, sticking the needle in does not hurt at all, at least not me. What hurts is the medicine (menopur the most) going in. It burns and I can feel it spreading. I have found that icing the area before hand helps tremendously. The tonal-F is not nearly as bad. But my IVF nurse had given me the advice to let the filled syringe sit for 10 minutes to come to room temp. I have done this and the pain is minimal.
But my tummy really hurts. I really do feel like a pin cushion. It feels slightly swollen, but hugely bruised. I am wearing looser clothing so as not to rub up against the area. Side effects are not too bad....some headaches and dizziness but only when I bend over, like to tie my shoe. And emotional. I feel like I want to cry over the silliest little things. Trying to keep that in check so as not to make my husband crazy.
Is it difficult? yes. Unbearable? No. I don't like it, but so far, it's nothing I can't handle. Still not trying to worry about if I will have enough eggs retrieved to do this, still not thinking about getting through all the cycles in my package and not getting pregnant. I have been searching my heart...Is this really worth it? Do I really want another baby. I can honestly and sincerely say yes. I want it as badly as ever.
And so ends cd 19.
Friday, 3 May 2013
Day one as a human pin cushion - drugs for IVF
Not much to report today. Absolutely nothing happened on cd 15 as I was waiting for my appt today. One minor note, I started spotting last night which had me slightly worried. But I thought it made sense seeing as I stopped the bcp's 2 days ago. The IVF nurse confirmed this was completely normal and nothing to worry about. Only other item of interest was this great big expensive box arrived on my doorstep. $4300 worth of fertility meds. I have to admit, even with all that money spent, it certainly did not feel like Christmas.
Had an early morning bloodwork and ultrasound. The bcp's did their job and everything looked good. They said my ovaries looked "fantastic"which made me laugh. I made the comment "at least something in my body is doing it's job!"
I do want to interject here. While not eating straight paleo, I have been strictly gluten free, and I do tend to try and lay off the grains. I think that has had a seriously positive impact on my ovaries. I've noticed on the ultrasounds, those "string of pearls" have been conspicuously absent. I think my inability to get pregnant really falls under either my age or that "unexplained" category.
Anyway, my "fantastic" ovaries were showing about 20-25 follicles on each side. I am hopeful that that means we will have a very successful retrieval.
Anyway, around 2:30 I got the call that everything looked good and my instructions for the weekend. I'll take 225 IU of the Gonal-F tonight, tomorrow and Sunday. In the mornings, I will take 3 vials of the menopur. Time to whip out these babies....
Don't they just look scary? The good news is, these are just used for mixing the menopur, NOT for injecting into me, thank goodness! The actual needle is much smaller, no bigger than an insulin needle. I'll try and remember to take a picture of it tomorrow so you can see.
Honestly, I was more nervous about mixing everything up. The vials actually come with the meds in a dry powder form, and you have to add a special water to it. But my IVF nurse had walked me through it, then suggested watching videos on youtube. So that's what I did, I laid everything out on my computer desk, watch the video and did my thing. It was just like an insulin shot (I had gestational diabetes with both boys) and it did not hurt one bit. I chose to do it myself into my stomach.
DH tried giving me insulin shots back when I was pregnant with both boys, and frankly he's horrible at it. He either jams it in (the man has strong Scottish genes) or loses his nerve at the last second and goes too slow. In any case, it hurts and I really am OK doing it myself.
So shots over the weekend, then I go in Monday to see what's happening. And that wraps cd 16.
Had an early morning bloodwork and ultrasound. The bcp's did their job and everything looked good. They said my ovaries looked "fantastic"which made me laugh. I made the comment "at least something in my body is doing it's job!"
I do want to interject here. While not eating straight paleo, I have been strictly gluten free, and I do tend to try and lay off the grains. I think that has had a seriously positive impact on my ovaries. I've noticed on the ultrasounds, those "string of pearls" have been conspicuously absent. I think my inability to get pregnant really falls under either my age or that "unexplained" category.
Anyway, my "fantastic" ovaries were showing about 20-25 follicles on each side. I am hopeful that that means we will have a very successful retrieval.
Anyway, around 2:30 I got the call that everything looked good and my instructions for the weekend. I'll take 225 IU of the Gonal-F tonight, tomorrow and Sunday. In the mornings, I will take 3 vials of the menopur. Time to whip out these babies....
Don't they just look scary? The good news is, these are just used for mixing the menopur, NOT for injecting into me, thank goodness! The actual needle is much smaller, no bigger than an insulin needle. I'll try and remember to take a picture of it tomorrow so you can see.
Honestly, I was more nervous about mixing everything up. The vials actually come with the meds in a dry powder form, and you have to add a special water to it. But my IVF nurse had walked me through it, then suggested watching videos on youtube. So that's what I did, I laid everything out on my computer desk, watch the video and did my thing. It was just like an insulin shot (I had gestational diabetes with both boys) and it did not hurt one bit. I chose to do it myself into my stomach.
DH tried giving me insulin shots back when I was pregnant with both boys, and frankly he's horrible at it. He either jams it in (the man has strong Scottish genes) or loses his nerve at the last second and goes too slow. In any case, it hurts and I really am OK doing it myself.
So shots over the weekend, then I go in Monday to see what's happening. And that wraps cd 16.
Thursday, 2 May 2013
Name that price! How much are the drugs?
So cycle day 14 brings the quest to actually acquire the drugs in my possession. I have to admit, I put it off as long as I could because I am still waiting for them to say "You are too old, go away. Your body is most certainly NOT a temple let alone an incubator for a little life. Go home!"
But they haven't. They continue to insist I have a chance at this. On Monday, if you recall, I had a very stressful day pricing everything. While it was upsetting and frustrating, I HIGHLY recommend this. Here's why. For the past how many years, they've always recommended Rosemont Pharmacy so of course I wasn't surprised to see it on my list of places to try. Their price for Gonal-F? $810 per vial. I need 5 vials for a total of $4050. Cornerstone in Willow Grove, the company I chose to go with? $384 a vial after they applied some sort of rebate (they applied for me and gave me the after rebate price). That totals $1920 for a savings of $2130! That's huge!
The other thing Cornerstone did was, they mentioned that cetrotide could be taken in place of Ganilrelex for a savings of $106.50 overall. So I called the nurses and asked if that was OK and it was - hooray!
The other good news is that I did indeed qualify for one of the Compassionate Care programs and they gave me 50% off the price paid for gonal-f and cetrotide. So take that off the prices listed above and I ended up with a total bill of $4300 instead of the $6000 ($7300 if I had gone with Rosemont) I was looking at before I started pricing. So do that if you can. These are all the cash out of pocket no insurance coverage prices by the way. I can't tell you what it looks like when insurance covers some or part.
My next challenge was paying for them. I had maxed out my credit card to pay for the IVF services last week and it was a race to see how quickly they would post the transaction my account, I could pay that electronically and set my balance back to 0. By 11:30am, my balance was back to 0 and I could call the pharmacy! It seems like everything is starting to fall into place now, and I am catching some of those breaks...like Compassionate Care taking pity on me and processing my application in 3 hours instead of 3-5 days.
I did have a back up plan. The worse case scenario is I would take the money out of my account in cash and drive the 2 hours to Cornerstone. But a) who wants to drive around with $4300 cash in their purse, and b) I wanted the credit card points. If I have to go through all this, I'm at least going to get an airline ticket to someplace warm and sunny out of it! ha ha ha
So after running to the UPS store to fax in the script, my Compassionate Care card, and my insurance card (there were three things that they thought they could get covered in my insurance - the antibiotic, the immunity rejection drug medol and the esterase -estrogen- that all have uses outside of fertility) and several back and forth calls, I am now patiently waiting for my big expensive box of drugs to arrive.
I am supose to start Friday. Again, I am compartmentalizing the ideas of all those shots, of what if this doesn't work, how many embryos to transfer, will I even get enough eggs to make embryos.. If I think too long on any of those, I start to get a little crazy. I noticed yesterday during my walk, that I made a conscious decision NOT to think about anything IVF related. I needed a break, and frankly, I think breaks away are good for me. I will take each day, and it's decisions, as they come.
And so ends cd 14.
Wednesday, 1 May 2013
BW, scan, Hysteroscopy, IVF Mock transfer and SA....Lions and tigers and bears, Oh My!
As you can see by the title, yesterday was a busy and let's be honest, scary day. Bloodwork and ultrasound were no big deal. I bet after 10 years of trying to have babies I've had at least 100 of each. Those turned out fine and yielded us good news. My estrogen was great, as was my progesterone... my system was "dimmed" as they put it, so I could stop the bcps (i had been on them 10 days total) and get ready to start the injectible drugs soon.
It was the after that, that had me so nervous. All the reports I had found online were scary. "Excruciating" "painful" "lasted forever" were just some of the keys phrases skyrocketing my blood pressure from it's healthy normal of 120/60 to a crazy high of 160/90 (um...the last time it was that high, they admitted me into the hospital and performed a c-section 20 minutes later!)
I have to stop and give kudos to my Dr. If you are in the philadelphia area, and are looking for a great RE - check out Dr. B. Gocial. He's amazing. He's never made me feel dumb for asking silly questions or being scared or anxious, and when you have bad news like a loss (or two) he is gentle and sympathetic.
So while I was shaking and on the verge of tears, he literally stops and touches my arm and says, "What exactly is scaring you?" in the most concerned tone. I flat out said, I was scared it would hurt, and I was scared he would find bad news and say "Sorry, game over, your uterus is a mess!"
He was very honest with me, described to process and indicated the discomfort wouldn't be bad, just talked about the cramping. Then he said, he's seen my uterus on ultrasound enough to know there probably really wasn't a problem. That he wouldn't even order it except we were doing an IVF and they just want to be sure.
I can hardly fault that logic. Yes, before I spend $25,000, I'd like to be sure too, that there's at least a chance!
So while I was still terrified, it helped to know my Dr. was sympathetic to my concerns. So I left the office and went to the adjoining surgical suite to wait my turn. Turned out, there were a lot of women "ready" so I had to wait while they performed FIVE retrievals! yikes, that's a lot of eggs!
My friend, "A" had said really the worst part about it was the "uncomfortably full" bladder you need to go with. OMG she was so right! That really was the worst part. I mean, how much do you actually have to drink to be "uncomfortably full?" I didn't want to not drink enough, and then they couldn't do it, but I've always been a bit of a camel, not needing to go to the bathroom too often. So I drank a glass of water when I awoke, a glass with breakfast, and grabbed a 24 ounce cup of decaf to drink on the way.
My eyes were yellow I was so "uncomfortably full."
And did I mention they were running behind schedule? Yikes! But finally it was my turn. The nurse was thankfully, very kind. I was led to a changing room with lockers. They had me change into a surgical gown, hair cover and footy socks (I love those socks with the little grippy things on the bottom... I had to contain myself from searching the cabinets to take home a stash of them). I locked my clothes, purse and phone in a locker and went out into the hallway.
The nurse greeted me almost immediately and led me back to a large room divided into three sections made into private rooms by hospital curtains. Instead of a bed was a large recliner chair covered in surgical pads. I took a seat, and they immediately gave me a warmed blanket to cover my legs. They went over my post-op instructions which was basically "go home, you're done" and then the, Dr. G checked on me once more.
In a few minutes they walked me into the OR. I took a seat on the table which is just a glammed up version of what's in the exam rooms. But the stirrups were much more robust and padded. And then it was time.
They did the mock transfer first. He inserted a speculum joking about how they haven't redesigned those things in 150 years. No kidding! I, like I'm sure most, really hate those things.... Do they have to be so heavy? Every time they put one in, I feel like it's pulling me down. I'm waiting for the day it does eventually fall out, pulling all my girly bits out with it....
Anyway, next was the insertion of the catheter. The only hard part about that was the nurse pushing down on my belly (read "uncomfortably full" bladder here) with the ultrasound device while he did the mock. It was over in about a minute, seriously. Felt much better when they were done pushing on the pee bag.
Next was the hysteroscopy. Huge deep breaths. I have a history of panic attacks, and I felt one coming on. My husband taught me to breath big deep breaths when this happens, and so that's what I did, and focused on relaxing. But really, it honestly was nothing. I felt some minor cramping, but honestly the HSG I had done 5 years ago pre-Noah, was much much worse. It was a little gross after, as the saline dripped out but it was done. And again, it took like maybe a minute or two at the most?
They did say I could spot so it was a little embarrassing when they asked me to scrunch the big paper covers between my legs and walk down the hallway to the bathroom. I prayed the husbands of other patients were all ensconced quietly behind the little curtains and they were.
And I was done. I went across the hall back to the changing room, got dressed and left. All that worrying for nothing. I wonder if the difference between those that had so much pain was that they hadn't had children before? I had been reading a blog where the woman said for her first child, it was excruciating, but the second one was nothing. I don't know, but it sounds like a good theory, anyway.
I was incredibly exhausted getting home, but I'm sure that's more about the emotional energy output and the lack of sleep from the night before. I did experience some cramping but it was closer to late afternoon. Nothing I couldn't stand, but let's just say I curled up on the couch and let DH make dinner for a change.
So that's it for cycle day 13. Tomorrow is the quest for drugs.
One final note, in all the blogs I found describing this experience, it was from the point of view of donor/adopted embryos. Just want to clarify that this will be a different process because we will be using my own eggs. So the drugs will be different as I prepare for the ER - egg retrieval.
It was the after that, that had me so nervous. All the reports I had found online were scary. "Excruciating" "painful" "lasted forever" were just some of the keys phrases skyrocketing my blood pressure from it's healthy normal of 120/60 to a crazy high of 160/90 (um...the last time it was that high, they admitted me into the hospital and performed a c-section 20 minutes later!)
I have to stop and give kudos to my Dr. If you are in the philadelphia area, and are looking for a great RE - check out Dr. B. Gocial. He's amazing. He's never made me feel dumb for asking silly questions or being scared or anxious, and when you have bad news like a loss (or two) he is gentle and sympathetic.
So while I was shaking and on the verge of tears, he literally stops and touches my arm and says, "What exactly is scaring you?" in the most concerned tone. I flat out said, I was scared it would hurt, and I was scared he would find bad news and say "Sorry, game over, your uterus is a mess!"
He was very honest with me, described to process and indicated the discomfort wouldn't be bad, just talked about the cramping. Then he said, he's seen my uterus on ultrasound enough to know there probably really wasn't a problem. That he wouldn't even order it except we were doing an IVF and they just want to be sure.
I can hardly fault that logic. Yes, before I spend $25,000, I'd like to be sure too, that there's at least a chance!
So while I was still terrified, it helped to know my Dr. was sympathetic to my concerns. So I left the office and went to the adjoining surgical suite to wait my turn. Turned out, there were a lot of women "ready" so I had to wait while they performed FIVE retrievals! yikes, that's a lot of eggs!
My friend, "A" had said really the worst part about it was the "uncomfortably full" bladder you need to go with. OMG she was so right! That really was the worst part. I mean, how much do you actually have to drink to be "uncomfortably full?" I didn't want to not drink enough, and then they couldn't do it, but I've always been a bit of a camel, not needing to go to the bathroom too often. So I drank a glass of water when I awoke, a glass with breakfast, and grabbed a 24 ounce cup of decaf to drink on the way.
My eyes were yellow I was so "uncomfortably full."
And did I mention they were running behind schedule? Yikes! But finally it was my turn. The nurse was thankfully, very kind. I was led to a changing room with lockers. They had me change into a surgical gown, hair cover and footy socks (I love those socks with the little grippy things on the bottom... I had to contain myself from searching the cabinets to take home a stash of them). I locked my clothes, purse and phone in a locker and went out into the hallway.
The nurse greeted me almost immediately and led me back to a large room divided into three sections made into private rooms by hospital curtains. Instead of a bed was a large recliner chair covered in surgical pads. I took a seat, and they immediately gave me a warmed blanket to cover my legs. They went over my post-op instructions which was basically "go home, you're done" and then the, Dr. G checked on me once more.
In a few minutes they walked me into the OR. I took a seat on the table which is just a glammed up version of what's in the exam rooms. But the stirrups were much more robust and padded. And then it was time.
They did the mock transfer first. He inserted a speculum joking about how they haven't redesigned those things in 150 years. No kidding! I, like I'm sure most, really hate those things.... Do they have to be so heavy? Every time they put one in, I feel like it's pulling me down. I'm waiting for the day it does eventually fall out, pulling all my girly bits out with it....
Anyway, next was the insertion of the catheter. The only hard part about that was the nurse pushing down on my belly (read "uncomfortably full" bladder here) with the ultrasound device while he did the mock. It was over in about a minute, seriously. Felt much better when they were done pushing on the pee bag.
Next was the hysteroscopy. Huge deep breaths. I have a history of panic attacks, and I felt one coming on. My husband taught me to breath big deep breaths when this happens, and so that's what I did, and focused on relaxing. But really, it honestly was nothing. I felt some minor cramping, but honestly the HSG I had done 5 years ago pre-Noah, was much much worse. It was a little gross after, as the saline dripped out but it was done. And again, it took like maybe a minute or two at the most?
They did say I could spot so it was a little embarrassing when they asked me to scrunch the big paper covers between my legs and walk down the hallway to the bathroom. I prayed the husbands of other patients were all ensconced quietly behind the little curtains and they were.
And I was done. I went across the hall back to the changing room, got dressed and left. All that worrying for nothing. I wonder if the difference between those that had so much pain was that they hadn't had children before? I had been reading a blog where the woman said for her first child, it was excruciating, but the second one was nothing. I don't know, but it sounds like a good theory, anyway.
I was incredibly exhausted getting home, but I'm sure that's more about the emotional energy output and the lack of sleep from the night before. I did experience some cramping but it was closer to late afternoon. Nothing I couldn't stand, but let's just say I curled up on the couch and let DH make dinner for a change.
So that's it for cycle day 13. Tomorrow is the quest for drugs.
One final note, in all the blogs I found describing this experience, it was from the point of view of donor/adopted embryos. Just want to clarify that this will be a different process because we will be using my own eggs. So the drugs will be different as I prepare for the ER - egg retrieval.
Subscribe to:
Posts (Atom)